Modulen Ibd Latte Polvere 400g

Product Information

Anti-TNF treatment is not all-encompassing despite its vital role in IBD treatment. Up to 40% of patients do not respond to TNF inhibitors, and nearly 23–46% of patients experience secondary loss-of-response 1 year after anti-TNF-α treatment ( 6). It may be possible to achieve long-term remission through dose escalation, shorter intervals between infusions ( 78) or combination therapy ( 79). Due to anti-TNF agents' dose-related therapeutic benefit, measurement of serum trough level and anti-drug antibody is advocated ( 80, 81). Anti-IL-12/23 Therapy Your diet can be helpful in managing your inflammatory bowel disease (IBD) during flares and periods of remission. Your healthcare team, including a registered dietitian specializing in IBD, may recommend a particular diet based on your symptoms.

Andersen V, et al. Fibre intake and the development of inflammatory bowel disease: A European prospective multi-centre cohort study (EPIC-IBD). J Crohns Colitis. 2018 Jan 24;12(2):129-136. Vasseur P, et al. Dietary Patterns, Ultra-processed food, and the risk of inflammatory bowel diseases in the NutriNet-Santé cohort. Inflamm Bowel Dis. 2021 Jan 1;27(1):65-73.

Group 1 received a free diet and a single donor standard fecal transplant (FT) by colonoscopy on day 1 and rectal enemas on days 2 and 14 without dietary conditioning of the donor. From the database's inception until October 2021, we conducted a comprehensive search in PubMed and Web of Science. The retrieval strategy is based on Medical Subject Headings (MeSH) and corresponding free words. The major search terms are as follows: “Inflammatory Bowel Disease,”“Bowel Diseases, Inflammatory,”“IBD,”“Crohn's Disease,”“Crohn's Enteritis,”“Ulcerative Colitis,”“Colitis Gravis,”“Aminosalicylates,”“Mesalazine,”“5-Aminosalicylic Acid,”“Corticosteroids,”“Thiopurines,”“Methotrexate,”“Calcineurin Inhibitors,”“Biologics,”“Janus Kinase inhibitors,”“Ozanimod,”“Etrasimod,”“Surgical Procedure,”“Apheresis,”“Blood Component Removals,”“Antibiotics,”“Antibacterial Agents,”“Probiotics,”“Prebiotics,”“Synbiotics,”“Postbiotics,”“Fecal Microbiota Transplantation,”“Stem Cell Transplantations,”“Exosomes,”“Diet.” The above search terms were connected by the logical operators “OR” or “And.” The research focused on the treatment of IBD. A total of 9,885 references were retrieved. Studies, which are old, repetitive and non-English and those without clear information were excluded. We selected some representative scientific papers and 257 references were finally quoted. Pharmacological Intervention

The return of symptoms during the maintenance phase can pose a challenge; however, this can often be related to the level of patient compliance and can be managed by a careful dietetic follow-up. The key message should remain that fibres are good for gut health and most patients should be consuming fibre. However, caution should still be made in advising fibre as different types of fibre may have different impacts on microbiota and inflammatory response. References A randomized controlled trial demonstrated that more than 80% of patients with severe acute refractory UC responded to CsA ( 58). It has been reported that the 8-day clinical remission rate (84.2 vs. 85.7%) of patients with severe UC treated with intravenous 4 mg/kg CsA is similar to that of patients treated with intravenous 2 mg/kg CsA ( 59). Stange et al. performed a randomized controlled trial to delineate the long-term effect of CsA on chronic active CD and found that CsA combined with low-dose steroids had no advantage over the sole use of low-dose steroids ( 60).

The study showed that CDED plus PEN was better tolerated than exclusive enteral nutrition (EEN) in children with mild to moderate CD. The combination of CDED plus PEN induced sustained remission in a significantly higher proportion of patients than EEN and produced changes in the fecal microbiome associated with remission. Suskind DL, Cohen SA, Brittnacher MJ, Wahbeh G, Lee D, Shaffer ML, Braly K, Hayden HS, Klein J, Gold B, Giefer M, Stallworth A, Miller SI. Clinical and Fecal Microbial Changes With Diet Therapy in Active Inflammatory Bowel Disease. J Clin Gastroenterol. 2018 Feb;52(2):155-163. doi: 10.1097/MCG.0000000000000772. M Szczubełek, Pomorska K, et al. Effectiveness of Crohn’s Disease Exclusion Diet for induction of remission in Crohn’s disease adult patients. Nutrients. 2021 Nov 17;13(11):4112.