Dietary glucoraphanin-rich broccoli sprout extracts protect against UV radiation-induced skin carcinogenesis in SKH-1 hairless mice. No ITCs were detected in either plasma or urine from subjects who consumed alfalfa sprouts or placebo pills. Sulforaphane has been shown to have anticancer properties in a number of test-tube and animal studies, reducing both the size and number of various types of cancer cells ( 5, 6, 7).

Dietary sulforaphane-rich broccoli sprouts reduce colonization and attenuate gastritis in Helicobacter pylori-infected mice and humans.The median effective dose of sulforaphane in the published literature by oral administration is 175 µmol/kg body weight and by intraperitoneal administration is 113 µmol/kg.

After 18 weeks, participants receiving sulforaphane experienced minimal change compared to those receiving the placebo. If any of these conditions is deemed invalid, void, or for any reason unenforceable, that condition will be deemed severable and will not affect the validity and enforceability of any remaining condition. Sulforaphane levels are higher when the vegetables are raw, these levels are lowered when cooked as it reduces the effectiveness of the myrosinase. Figure 2 highlights the distributions of doses selected by investigators for oral or intraperitoneal dosing to mice. Safety considerations: High doses may cause sedation, impair motor coordination, and decreased muscle strength.

While Evolution Organics strives to ensure the accuracy of its product images and information, some manufacturing changes to packaging and/or ingredients may be pending update on our site. Broccoli sprout extract induces detoxification-related gene expression and attenuates acute liver injury.