Studies conducted on human subjects and animals demonstrate chlorhexidine gluconate is poorly absorbed from the gastrointestinal tract. The mean plasma level of chlorhexidine gluconate reached a peak of 0.206 µg/g in humans 30 minutes after they ingested a 300-mg dose of the drug. Detectable levels of chlorhexidine gluconate were not present in the plasma of these subjects 12 hours after the compound was administered. Excretion of chlorhexidine gluconate occurred primarily through the feces (~90%). Less than 1% of the chlorhexidine gluconate ingested by these subjects was excreted in the urine. PerioGard ® can cause staining of oral surfaces, such as tooth surfaces, restorations, and the dorsum of the tongue. Not all patients will experience a visually significant increase in tooth staining. In clinical testing, 56% of the chlorhexidine gluconate oral rinse users exhibited a measurable increase in facial anterior stain, compared to 35% of control users after six months; 15% of the chlorhexidine gluconate users developed what was judged to be heavy stain, compared to 1% of control users after six months. Stain will be more pronounced in patients who have heavier accumulations of unremoved plaque. Stain resulting from the use of PerioGard ® does not adversely affect health of the gingivae or other oral tissues. Stain can be removed from most tooth surfaces by conventional professional prophylactic techniques. Additional time may be required to complete the prophylaxis. Discretion should be used when prescribing to patients with anterior facial restorations with rough surfaces or margins. If natural stain cannot be removed from these surfaces by a dental prophylaxis, patients should be excluded from PerioGard ® treatment if permanent discoloration is unacceptable. Stain in these areas may be difficult to remove by dental prophylaxis and, on rare occasions, may necessitate replacement of these restorations. PerioGard® (Chlorhexidine Gluconate Oral Rinse USP, 0.12%) provides antimicrobial activity during oral rinsing. The clinical significance of chlorhexidine gluconate oral rinse’s antimicrobial activities is not clear. Microbiological sampling of plaque has shown a general reduction of counts of certain assayed bacteria, both aerobic and anaerobic, ranging from 54-97% through six months’ use. The most common side effects associated with chlorhexidine gluconate oral rinse USP, 0.12% are: (1) an increase in staining of teeth and other oral surfaces, (2) an increase in calculus formation, and (3) an alteration in taste perception; see WARNINGS and PRECAUTIONS. Oral irritation and local allergy-type symptoms have been spontaneously reported as side effects associated with use of chlorhexidine gluconate rinse. The following oral mucosal side effects were reported during placebo-controlled adult clinical trials: aphthous ulcer, grossly obvious gingivitis, trauma, ulceration, erythema, desquamation, coated tongue, keratinization, geographic tongue, mucocele, and short frenum. Each occurred at a frequency of less than 1.0%.

COLGATE PerioGard Chlorhexidine 0.12% Mouthwash 300ml Gum COLGATE PerioGard Chlorhexidine 0.12% Mouthwash 300ml Gum

Store at 20 o to 25 oC (68 o to 77 oF); excursions permitted between 15 o to 30 oC (59 o to 86 oF) [see USP Controlled Room Temperature]. Pediatric Use: Clinical effectiveness and safety of PerioGard® have not been established in children under the age of 18. Experience whitening beyond the ordinary when you brush with Colgate Max White Ultra Freshness Pearls Whitening Toothpaste. The Colgate Link toothbrush is good for you and good for the planet! The whitening replacement toothbrush heads can only be used with the Colgate Link Aluminium handle and have advanced head technology with stain removing cups that help to reduce surface stains on your teeth whilst giving you a whiter smile from the very first brushing. Thanks to the replaceable heads, it has 80% less plastic* . Looking after your teeth and the planet will give you even more reasons to flash your bright smile. vs a regular plastic manual toothbrush Look after your enamel and keep your bright smile brilliantly protected with Colgate Total Advanced Enamel Strength Toothpaste.Ingestion of 1 or 2 ounces of PerioGard ® (Chlorhexidine Gluconate Oral Rinse USP, 0.12%) by a small child (~10 kg body weight) might result in gastric distress, including nausea, or signs of alcohol intoxication. Medical attention should be sought if more than 4 ounces of PerioGard ® oral rinse is ingested by a small child or if signs of alcohol intoxication develop. Colgate’s most advanced mouthwash provides 24 hour* protection against germs after eating or drinks. All fluoride containing toothpastes are regulated by the U. S. Food and Drug Administration (USFDA). We put an expiration date on our products that coincides with our product stability testing results and depending on the product, it varies from 18 to 24 months after manufacturing date. After this time has elapsed, the fluoride and aesthetic aspects (i.e. flavor, consistency) may diminish. Therefore, even though the toothpaste is not harmful, we do not recommend using it. Often the first signs are recognised too late and not treated in time. The consequences can be irreparable. The health of the gums and teeth can also have an impact on general wellbeing.

Colgate PerioGard Gum ProtectionToothpaste 75ml | Gum health Colgate PerioGard Gum ProtectionToothpaste 75ml | Gum health

PerioGard ® (Chlorhexidine Gluconate Oral Rinse USP, 0.12%) is indicated for use between dental visits as part of a professional program for the treatment of gingivitis as characterized by redness and swelling of the gingivae, including gingival bleeding upon probing. PerioGard ® oral rinse has not been tested among patients with acute necrotizing ulcerative gingivitis (ANUG). For patients having coexisting gingivitis and periodontitis, see PRECAUTIONS. https://www.mayoclinic.org/drugs-supplements/chlorhexidine-oral-route/side-effects/drg-20068551? p=1#:~:text=Chlorhexidine%20is%20used%20to%20treat,your%20teeth%20between%20tooth%20brushings PerioGard® is supplied as a blue liquid in a 16-fluid ounce (473 mL) (NDC 0126-0272-16) amber plastic bottle with child-resistant dosage cap. Colgate’s first Max White purple toothpaste reveals an instantly* whiter smile. It contains optic colour-correcting technology to correct yellow tones & is safe for your enamel. *Effect is temporary. Pregnancy: Teratogenic Effects: Reproduction studies have been performed in rats and rabbits at chlorhexidine gluconate doses up to 300 mg/kg/day and 40 mg/kg/day, respectively, and have not revealed evidence of harm to the fetus. However, adequate and well controlled studies in pregnant women have not been done. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed.Reduces certain aerobic and anaerobic bacteria counts from 54-97% through six months’ clinical use2 Chlorhexidine 0.12% prolonged usage** and its unique formula with anti-bacterial action and anti-stain system is ideal for reduced*** chlorhexidine-related teeth staining. The effect of PerioGard® on periodontitis has not been determined. An increase in supragingival calculus was noted in clinical testing with users of chlorhexidine gluconate oral rinse USP, 0.12% compared with control users. It is not known if chlorhexidine gluconate use results in an increase of subgingival calculus. Calculus deposits should be removed by a dental prophylaxis at intervals not greater than six months. Anaphylaxis, as well as serious allergic reactions, have been reported during postmarketing use with dental products containing chlorhexidine. SEE CONTRAINDICATIONS.

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Colgate Link Deep Clean Replaceable Head Toothbrush has been beautifully designed with a premium aluminium handle that you can use and reuse for as long as you like. It's advanced head technology with floss-tip bristles that reach 4X* deeper to gently clean between teeth and along the gumline for a healthy smile. The Colgate Link toothbrush is good for you and good for the planet. Thanks to the replaceable heads, it has 80% less plastic **. Looking after your teeth and the planet will give you even more reasons to flash your bright smile. *Below the gumline compared to an ordinary flat trim toothbrush ** vs a regular plastic manual toothbrush Carcinogenesis, Mutagenesis, Impairment of Fertility: In a drinking water study in rats, carcinogenic effects were not observed at doses up to 38 mg/kg/day. Mutagenic effects were not observed in two mammalian in vivo mutagensis studies with chlorhexidine gluconate. The highest doses of chlorhexidine used in a mouse dominant-lethal assay and a hamster cytogenetics test were 1000 mg/kg/day and 250 mg/kg/day, respectively. No evidence of impaired fertility was observed in rats at doses up to 100 mg/kg/day Use of chlorhexidine gluconate oral rinse USP, 0.12% in a six-month clinical study did not result in any significant changes in bacterial resistance, overgrowth of potentially opportunistic organisms or other adverse changes in the oral microbial ecosystem. Three months after chlorhexidine gluconate oral rinse USP, 0.12% use was discontinued, the number of bacteria in plaque had returned to baseline levels and resistance of plaque bacteria to chlorhexidine gluconate was equal to that at baseline. Colgate ®PerioGard SFis a daily toothpaste that fights the bacteria that can cause early gum disease. This specialized formula significantly reduces gum bleeding and inflammation, and delivers long lasting gum protection with continued use. Healthy Smiles With ColgateThe unique dual active formula has a lasting antibacterial effect**. The active ingredients are spread around the oral cavity instantly and start working immediately. It lastingly inhibits bacterial plaque build-up, effectively protecting from gum problems. Long-lasting antibacterial effect** Try Colgate Max White Ultra Active Foam Whitening Toothpaste. Clinically proven to give you whiter teeth in 3 days. At Colgate we believe everyone deserves a future to smile about. Championing optimism means we are committed to creating a healthier planet and work every day to create healthy smiles for all. I used another leading brand for my dodgy gums and wasnt too impressed as turned my teeth yellow and didnt really help with the bleeding. The flavor was also horrid. I swapped to this and its a much better product. Taste nice and really seems to work.

Colgate Perio Gard Gum Protection Sensitive Toothpaste 75Ml

Aqua, Xylitol, Hydrated Silica, Glycerin, Sodium Methyl Cocoyl Taurate, Tetrasodium Pyrophosphate, Aroma, Zinc Phosphate; Cellulose Gum, Sodium Citrate, Microcrystalline Cellulose, Cocamidopropyl Betaine, Stannous Fluoride, Sodium Saccharin, Sucralose, Limonene, CI 74160.PerioGard ® should not be used by persons who are known to be hypersensitive to chlorhexidine gluconate or other formula ingredients. Colgate makes many different types of toothpastes which serve different purposes. Some whiten, some desensitize, some prevent, and pretty much all of them freshen and protect. PerioGard Gum Protection mouthrinse helps to fight the cause of gum problems* and irritation, before it occurs. It doesn't just fight the symptoms. At Colgate, we make toothpaste that promotes healthy smiles. Not only because having a healthy smile is important to your overall health, but because when you have a healthy smile, you actually smile more – and that’s a powerful thing. Smiles are the simplest form of optimism, something we need now more than ever. That’s why we’re committed to raising oral healthcare standards everywhere. PerioGard Gum Care Toothpaste Benefits Brighten your smile with Colgate® Max White Ultimate Catalyst - our most effective whitening toothpaste, removing up to 15 years of discolouration.